Biological Activity of Natural Products by Jaroslava Svarc-Gajic

By Jaroslava Svarc-Gajic

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Pekić B. Hemija i tehnologija farmaceutskih proizvoda (alklaoidi i etarska ulja). Tehnološki fakultet, Novi Sad, 1983. Riguera R. Isolating bioactive compounds from marine organisms. J Mar Biotech 5, 1997, 187-193. Roh SS, Lee MH, Hwang YL, Song HH, Jin MH, Park SG, Lee CK, Kim CD, Yoon TJ, Lee JH. Stimulation of the extracellular matrix production in dermal fibroblasts by velvet antler extract. Ann Derm. 22(2), 2010,173179. Švarc-Gajić J. Naturally occurring food toxicants. In: Nutritional insights in food safety (Ed: Švarc-Gajić J.

A macrolide lactone with immunomodulating properties was isolated from Streptomyces tsukubaensis. 5), an immunosuppressant used after organ transplantation. The drug functions by reducing interleukine-2 production and is also applicable in the treatment of vitiligo and eczema. 5. Tacrolimus, an immunosuppressant drug. 3. Bioactive Compounds of Animal Origin Deer antlers grow rapidly in the spring with the rate of few centimeters each day. This period of intensive cell growth lasts several months.

PHYTOESTROGENS Phytoestrogens are naturally occurring non-steroidal compounds which have been identified in more than 300 plant species. Their bioactivity arises from mimicking biochemical effects of estrogen. Phytoestrogens act as agonists or antagonists of 17-β-estradiol. Flax seed and soybeans have been identified as food containing among the highest levels of phytoestrogens. Flavones, Isoflavones, lignans and coumestans are major classes of phytoestrogens. Isoflavones are found in high concentration in soy products, whereas in flax seed lignans are predominant.

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