Alkaloids: Biochemistry, Ecology, and Medicinal Applications by Margaret F. Roberts

By Margaret F. Roberts

Not because the past due Nineteen Seventies has a unmarried paintings awarded the biology of this heterogenous team of secondary alkaloids in such intensity. Alkaloids, a special treatise that includes leaders within the box, offers either the historic use of alkaloids and the newest discoveries in

  • the biochemistry of alkaloid creation in vegetation
  • alkaloid ecology, together with marine invertebrates, animal and plant parasites, and
  • alkaloids as antimicrobial and present medicinal use

. Highlights comprise chapters at the chemical ecology of alkaloids in host-predator interactions, and at the compartmentation of alkaloids synthesis, delivery, and garage. broad cross-referencing in tabular structure makes this quantity an outstanding reference.

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Extra resources for Alkaloids: Biochemistry, Ecology, and Medicinal Applications

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Even Shakespeare refers to this phenomenon in a scene where Juliet takes the sleeping potion. 23. Nicotiana tabacum (Family Solanaceae) N. tabacum and related species originate from America and accumulate the pyridine alkaloid nicotine (44) and related compounds in all tissues. Nicotine activates the acetylcholine receptor (termed "nicotinic AChR") and is stimulatory for the central and vegetative nervous system at lower doses. Higher doses are rather toxic (50-100 mg of nicotine is lethal for humans), leading to paralysis and death caused by respiratory failure.

An Egyptian recipe of the goddess Isis for the god Ra includes opium ("Xasit") as a remedy against headache. The ancient Greeks and Romans knew the plant well. ) and Dioscorides described the harvest of opium by cutting the unripe poppy fruits. The latter gave an excellent description on the medicinal properties of opium (which is more or less even valid today): A pea-sized piece of opium kills pain effectively, induces sleep, activates digestion, silences cough and stomach troubles. Applied on the head (together with rose oil) opium helps against headache, and mixed with almond oil, saffron, and myrrh helps against earache, when brought into the auditory channel.

3. Areca catechu (Family Arecaceae) Areca is a palm that occurs in Southeast Asia. , arecoline activates the muscarinic AChR (see Chapter 12). In Southeast Asia and East Africa, Areca seeds are ingested as "betel," which is a combination of leaves of the vine Piper betel, slices of Areca seeds, and lime. For several hundred years, it has been a common habit of more than 200 million people to chew betel. The alkaloids, which are converted into the free base in the buccal cavity, are directly absorbed and quickly pass the blood-brain barrier.

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